The drive between Puebla City and Oaxaca City is an easy one, just over 4 hours on the autopista (Mexican toll roads 150D and 135D). And most people who have traveled along this route will tell you it’s a beautiful drive. But by taking this route, you’ve just bypassed some really amazing stuff.
Here is an alternative route, for those of you who want to take the time to discover seldom-visited places for yourself.